Protein Modification Reagents
![Medchemexpress LLC Ethanol, 2-[2-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]ethoxy]- | 1807520-99-5 | 97.9% | C14H21N3O8 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Ethanol, 2-[2-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]ethoxy]- | 1807520-99-5 | 97.9% | C14H21N3O8 | 250 MG
DNP-PEG4-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Facilitates selective degradation of target proteins.
Medchemexpress LLC DSPE-PEG-FITC | 1000788-53-3 | 98.1% | 5000 Da (average) | 10 MG
DSPE-PEG-FITC (MW 5000) is a fluorescein-conjugated polyethylene glycol (PEG) lipid amphiphile designed for fluorescent labeling of liposomes, nanoparticles, and biological samples. It combines a DSPE lipid anchor with an FITC-labeled PEG chain to provide stable fluorescence for imaging and tracking applications. Supplied as a light yellow solid, handle and store per manufacturer guidance.
- Provides fluorescein (FITC) fluorescence for detection and imaging.
- Average PEG molecular weight ≈ 5,000 Da.
- Amphiphilic PEG-lipid suitable for incorporation into liposomes and micelles.
- High purity suitable for research use.
- Light yellow solid physical form for easy handling.
- Storage recommendations available for powder and solutions.
Medchemexpress LLC NH-bis(PEG4-Boc) | 2055041-41-1 | 98.0% | C30H59NO12 | 50 MG
NH-bis(PEG4-Boc) is a chemical compound primarily intended for research use. It is identified as 4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 1,31-bis(1,1-dimethylethyl) ester.
- Purity (NMR): 98.0%
- Molecular formula: C30H59NO12
- Molecular weight: 625.79
- Appearance: Colorless to light yellow liquid
- Recommended storage: 4°C, protect from light. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light).
![eMolecules 2222687-71-8 | Biotin-PEG4-Picolyl azide | Broadpharm | MFCD29052186 | 622.740 | C27H42N8O7S | 95.000 | [N-]=[N+]=NCc1ccc(NC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cn1 | 5mg | 296213266](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502471153.JPG-250.jpg)
eMolecules 2222687-71-8 | Biotin-PEG4-Picolyl azide | Broadpharm | MFCD29052186 | 622.740 | C27H42N8O7S | 95.000 | [N-]=[N+]=NCc1ccc(NC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cn1 | 5mg | 296213266
Biotin-PEG4-Picolyl azide | Broadpharm | 2222687-71-8 | MFCD29052186 | 622.740 | C27H42N8O7S | 95.000 | [N-]=[N+]=NCc1ccc(NC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cn1 | 5mg | 296213266
Ubpbio TCEP Powder, 25 GR, CAS# 51805-45-9
Reducing Agents - TCEP - TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides.
Medchemexpress LLC N6-(1-carboxyethyl)-L-lysine | 5746-03-2 | MFCD30364298 | 99.9% | 218.25 | C9H18N2O4 | 10 MG
Nε-(Carboxyethyl)lysine (CEL) is an advanced glycation end product used in biochemical and cellular research to study protein glycation, receptor for AGE (RAGE) signalling, and related pathological processes. It is supplied as a white to off-white solid with high analytical purity for laboratory applications.
- High purity (99.9%) suitable for analytical and cellular studies.
- Used to model advanced glycation end product formation and protein cross-linking.
- Interacts with RAGE receptor pathways to study inflammatory signaling.
- Modulates glutamate transporters and affects neurotransmission-related assays.
- Characterized chemical identity with CAS 5746-03-2 and defined molecular weight.
- Provided as a solid for ease of handling and storage.
- For research use only; not for human or clinical use.
AdipoGen TCEP (5 g)
Chemical. CAS: 51805-45-9. Formula: C9H15O6P·HCl. MW: 286.60. TCEP is an odorless, selective, and water-soluble strong reducing agent that is commonly used in biochemistry and molecular biology applications. It is commonly used to rapidly reduce protein and peptide disulfide bonds a preparatory step for gel electrophoresis. TCEP can be combined with proteases to simultaneously reduce and digest proteins prior to mass spectrometry in order to dramatically increase sequence coverage. More stable than DTT and useful in mass spectrometry applications. It has also been used to measure ascorbic acid and dehydroascorbic acid in biological samples. TCEP is a useful chelating agent for various heavy metal ions as Zn(II), Cd(II), Pb(II), and Ni(II).
Medchemexpress LLC Carboxyethyl-γ-aminobutyric acid | 4386-03-2 | MFCD00057954 | 175.18 g/mol | C7H13NO4 | 10 MG
Carboxyethyl-γ-aminobutyric acid is a small-molecule biochemical reagent supplied as a powder for laboratory research. Identified by CAS 4386-03-2, it has formula C7H13NO4 and molecular weight 175.18 g/mol. Store and handle according to the safety data sheet and product documentation.
Medchemexpress LLC L-dithiothreitol | 16096-97-2 | MFCD00064305 | 98.0% | 154.25 g·mol⁻¹ | C4H10O2S2 | 10 MG
L-dithiothreitol (DTT) is a small-molecule thiol reducing agent used to cleave disulfide bonds and maintain cysteine residues in the reduced state during biochemical and molecular biology workflows. It is commonly used in sample preparation, protein analysis, and enzymatic assays.
- Effective reducing agent for cleaving disulfide bonds.
- Helps maintain proteins in a reduced, active state.
- Soluble in water and compatible with common buffers.
- High purity suitable for biochemical applications.
- Available in small quantities for analytical and research use.
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol >=99.0% (RT) | 3483-12-3 | MFCD00004877 | 25G
DL-Dithiothreitol >=99.0% (RT) | Purity: >=99.0% (RT) | Mol Wt: 154.25 | 3483-12-3 | MFCD00004877 | 25G
Sino Biological Assay Buffer and Co-factors: DTT Solution
0.1 M DTT solution used for preparing protein kinase assay buffer.